The University of Virginia Comprehensive Cancer Center seeks an experienced laboratory technician/specialist with expertise in investigation of new investigational therapies in small animal (murine) models.

The appropriate candidate should have at least an undergraduate or master degree in biology or related fields, with at least 2 to 3 years of laboratory experience. The appropriate candidate must have direct working experience with studies involving small animal (murine) models. Responsibilities include conducting in vivo drug studies in cancer xenograft mouse model (both subcutaneous and orthotopic models), intravenous and intraperitoneal injections of drugs, drawing blood for analytical studies, experience with necropsy and tissue sampling, and sample preparation/analysis in downstream assays such as immunohistochemistry, flow cytometry, Western blot, qPCR, and RNAseq. Working experience with other species (rats and dogs) and writing and managing animal care protocols for research beneficial but not required.

Other experiences related to understand the activity of cancer drugs beneficial. This includes investigating drug effect on cells in tissue culture as well as a familiarity in studying mechanism of action of drugs and/or biologics in in vitro models of cancer. Candidates with expertise using more sophisticated molecular techniques like CRISPR, gene expression studies, confocal microscopy, and other molecular assays are highly encouraged to apply, though lack experience with these techniques is not exclusionary.

The candidate will be fully integrated into a well-funded (R01, American Cancer Society Research support, major funding through the Translational Orphan Blood Cancer Research Initiative) world-class laboratory with over 30 years of experience conducting state-of-the-art research and drug discovery and development focused on blood cancers. Successful candidates must have effective communication skills as evidenced by favorable team interactions. Professional development and career advancement opportunities will be strongly supported. The candidate will report directly to Owen A. O'Connor, M.D., Ph.D. in the Department of Medicine, Division of Hematologic Oncology.

MINIMUM REQUIREMENTS:

Laboratory and Research Technician 2

Education: Associate's degree

Experience: At least 2 years of lab experience which may include student experience. Bachelor's degree in related science will be considered in lieu of experience.

Lab Specialist:

Education: Bachelor's degree.

Experience: 2 years of experience. 4 years of lab-related experience accepted in lieu of degree.

PHYSICAL DEMANDS

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.

Salary will be commensurate with education and experience. This is a non-exempt-level, benefited position. Learn more about UVA benefits . This is a restricted position, which is dependent on funding and is contingent upon funding availability.

This position is based in Charlottesville, VA, and must be performed fully on-site. To learn more about UVA and in the Charlottesville area, visit UVA Life and Embark CVA .

Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.

HOW TO APPLY

Please apply online , by searching for requisition number R0074396. Complete an application with the following documents:

Resume
Cover Letter

Internal applicants can search and apply for jobs on the UVA Internal Careers website .

Upload all materials into the resume submission field. You can submit multiple documents into this one field or combine them into one PDF. Applications without all required documents will not receive full consideration.

Reference checks will be completed by UVA's third-party partner, SkillSurvey, during the final phase of the interview. For questions about the application process, please contact Jeremy Brofft, Senior Recruiter at xmf9ad@virginia.edu .

Job Profile

J1883 - Laboratory Research Operations and Service 2

Career Stream and Level

Operations and Service-O2

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment .

State of Virginia

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Lab and Research Technician 2 or Specialist