Zoetis is currently looking for a Protein Expression Senior Associate Scientist to join our team in Kalamazoo, MI. The Protein Sciences group within Zoetis Discovery Sciences and Technologies (DST) has the responsibility of delivering high quality, purified novel biotherapeutics and reagents for a diverse array of indications across our portfolio. We are seeking a talented and experienced scientist to join our protein expression team. In this role the individual will be responsible for production of various proteins from both mammalian and bacterial expression systems. The ideal candidate will have strong cell and molecular biology experience, and a demonstrated ability to work independently with a variety of cell lines using both transient and stable systems.
Essential Duties and Responsibilities:
- Prokaryotic and eukaryotic expression (both transient and stable) of recombinant gene constructs.
- Conduct small to large scale protein production runs to generate material to support discovery, in-vitro and in-vivo assay development and early development of novel therapeutic molecules.
- Construct expression vectors that will be used to generate stable pools expressing proteins of interest.
- Prepare precise technical report summaries, protocols, analysis and maintain appropriate documentation.
- Maintain high scientific rigor and attention to detail in testing hypotheses and analyzing data.
- Represent the Protein Sciences team and present relevant data at project team meetings.
Basic Qualifications:
- Bachelor’s degree with emphasis in cell biology, molecular biology or related field with 1+ years of hands-on experience.
- Training and demonstrated proficiency in cell biology and aseptic cell culture with a wide variety of cell types.
Preferred:
- Master’s degree preferred
- Ability to work independently and as part of a team, exhibiting self-motivation, adaptability, and a positive attitude.
- Attention to detail and good oral and written communication skills required.
- Knowledge and proficiency in molecular biology and protein analysis techniques (SDS-PAGE, Western Blot) – hands on experience preferred.
- Recombinant protein expression experience in prokaryotic (E. coli) and eukaryotic (yeast, mammalian) systems - preferred
- Experience in the generation and functional assessment of recombinant cell lines expressing various target proteins is a plus
Full timeRegularColleague
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